Dual host specificity of phage SP6 is facilitated by tailspike rotation
نویسندگان
چکیده
منابع مشابه
Carbohydrate binding of Salmonella phage P22 tailspike protein and its role during host cell infection.
TSPs (tailspike proteins) are essential infection organelles of bacteriophage P22. Upon infection, P22TSP binds to and cleaves the O-antigen moiety of the LPS (lipopolysaccharide) of its Salmonella host. To elucidate the role of TSP during infection, we have studied binding to oligosaccharides and polysaccharides of Salmonella enterica Typhimurium and Enteritidis in vitro. P22TSP is a trimeric ...
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A full set of SP6 promoter variants with all possible single substitutions at positions -17 to +5 was constructed. Transcription activities of these variants were individually measured in vivo and in vitro to determine the contribution of each base pair to the promoter activity. The in vivo activity was measured indirectly by transcriptional interference of the replication of promoter-bearing p...
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ژورنال
عنوان ژورنال: Virology
سال: 2017
ISSN: 0042-6822
DOI: 10.1016/j.virol.2017.04.017